Metadata
| Creators: | Zhang, Xuming | ||||
|---|---|---|---|---|---|
| Keywords: | TRPM8, PIP2, bradykinin, G protein, GPCR signaling, protein-protein interaction, Pain, inflammation | ||||
| Divisions: | College of Health and Life Sciences > Clinical and Systems Neuroscience | ||||
| Funders: | Medical Research Council, Aston University | ||||
| Projects: | Regulation of termo-TRP ion channels | ||||
| Grant number: | G0801387, 49294 | ||||
| Data Publisher: | Aston University | ||||
| Date Made Available: | 29 May 2019 | ||||
| Collection period: |
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| Data Collection and Processing Methods: | Zhang X dataset is the quantification and measurement of TRPM8 firing, currents and fluorescence signals under different conditions. The data were collected with electrophysiological recordings and confocal imaging of single cells. TRPM8-Gq modelling is the proposed structural interaction between TRPM8 and Galpha q using the Discovery studio 4.0 software. The data were collected for elucidating the mechanisms of TRPM8 modulation and gating. | ||||
| Identification Number: | https://doi.org/10.17036/researchdata.aston.ac.uk.00000427 |
Zhang, Xuming (2019) Data underpinning article "Direct Galpha q gating is the sole mechanism for TRPM8 inhibition caused by bradykinin receptor activation". [Dataset] Aston University. Available from: https://doi.org/10.17036/researchdata.aston.ac.uk.00000427
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