Fixed Dose Combination Orally Disintegrating Tablets to Treat Cardiovascular Disease: Formulation, in vitro Characterization and Physiologically Based Pharmacokinetic Modelling to Assess Bioavailability

Metadata

Creators: Dennision, Thomas, Smith, Julian, Badhan, Raj and Mohammed, Afzal
Keywords: Orally disintegrating tablet, Fixed dose combination, Cardiovascular disease, Physiologically based pharmacokinetic modelling, Bioavailability, Bioequivalence
Divisions: College of Health and Life Sciences > Applied Health Research Group (AHRG)
Funders: Medical Research Council
Grant number: MR/J01236X/1
Data Publisher: Aston University
Date Made Available: 3 February 2017
Collection period:
FromTo
May 2016September 2016
Data Collection and Processing Methods: The Excel files contain dissolution data for both single and FDC formulations, which have been corrected for samples withdrawn under sink conditions. Data is also included for Caco-2 drug permeability studies and show the mass transfer of drug from both A-B and B-A directions over the study period
Identification Number: https://doi.org/10.17036/researchdata.aston.ac.uk.00000178

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Atorvastatin Fasted Single SUMMARY.xlsx
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Atorvastatin Fed Combined.xlsx
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